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SF SPCA Adoption Center
250 Florida Street
San Francisco CA 94103
415-522-3500
Closed Mondays
and major holidays.
Tuesday – Friday, 1:00 p.m. – 7:00 p.m.
Saturday – Sunday, 10:00 a.m. – 6:00 p.m.
Note: We cannot guarantee we will be able to process an adoption the same day if paperwork is presented to the adoption desk later than 1 hour before closing, or if there are already many clients waiting.
Free parking

From the North Bay
Take Highway 101 across the Golden Gate Bridge. Stay on 101 heading south, and exit at Lombard. Take Lombard (approximately 12 blocks) to Van Ness. Make a right turn on Van Ness and follow for approximately 2 miles, all the way across Market Street (where the street turns into South Van Ness). Continue on for four blocks until you reach 16th Street. Make a left onto 16th Street. Travel 2-1/2 blocks down 16th Street and make a left on Florida Street.
From the East BayTake I-80 West across the Bay Bridge. Exit at 9th Street Civic Center offramp. Make a wide left turn onto Harrison (a multi-lane, 1-way Street). Follow for approximately 6 blocks, to 16th Street. Make a left onto 16th Street. Travel 2-1/2 blocks down 16th Street and make a left on Florida Street.
From the Peninsula
Take Highway 101 (or 280 north to the 101) north. Exit at the Vermont Street offramp. Make first left onto Vermont Street. Follow 2 blocks downhill to 16th Street. Make a left onto 16th Street. Travel 2-1/2 blocks down 16th Street and make a right on Florida Street.